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September 28, 2010 | Tuesday 
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Human Subjects
Study on Bulkamid for Treatment of Stress Urinary Incontinence

The Division of Female Pelvic Medicine and Reconstructive Surgery at the Miller School is conducting a study on Bulkamid, an investigational urethral bulking agent for minimally invasive treatment of stress urinary incontinence. You may be eligible for this study if you are seeking treatment for stress urinary incontinence (involuntary leakage of urine during physical activity such as sneezing, coughing or laughing). For more information, please contact Iliana Rivas at 305-243-5774.


Study on Acne in Men

The Department of Dermatology and Cutaneous Surgery is recruiting healthy male patients, ages 18 to 35, who previously had acne, but now have clear skin and are not taking medications. The experimental study will examine whether chocolate has an effect on acne. If you are interested in participating, please call the skin research group at 305-243-5519 for more information. You will be compensated for your time.


Genetic Differences Within the Latin American and Caribbean Populations

Help us learn more about the genetic differences within the Latin American and Caribbean populations by participating in a research study.

The University of Miami research team at the John P. Hussman Institute for Human Genomics is interested in individuals of Latin American or Caribbean descent whose parents are still living. An individual may qualify for the study if at least three out of the four grandparents were born in one of the following countries: Cuba, Dominican Republic, Haiti, Honduras or Puerto Rico. Participation involves less than an hour. Trained staff will perform a brief medical history interview, ask a few questions about family ethnicity and draw a blood sample.

Participants will be compensated for their time ($75 per family or $25 each individual). Please call 1-877-686-6444 for more information or visit www.hihg.org.


Alzheimer’s Disease in African-American and Other Black Populations

Researchers at the John P. Hussman Institute for Human Genomics, led by Margaret Pericak-Vance, Ph.D., the Dr. John T. Macdonald Foundation Professor of Human Genomics and director of the Hussman Institute, are working to find the genetic causes of Alzheimer's disease. The goal of the research is to improve methods for diagnosis and treatment of Alzheimer's.

African-American and other black populations have been underrepresented in Alzheimer's research studies and may be especially at risk because of diabetes, high blood pressure and high cholesterol. To address this disparity and improve research, the Hussman Institute is conducting a study of Alzheimer's in these populations.

Participants may be compensated. There are no costs or travel involved and participation is confidential. For more information, please call 1-877-686-6444, or visit www.hihg.org.


Post-Menopausal Women Needed for Study to Examine Impact of Exercise On Weight Loss

UM's Department of Exercise and Sport Sciences is looking for post-menopausal women for a research study to compare the effects of different types of exercise on weight loss. To be eligible, individuals should be post-menopausal for at least one year, not currently involved in a regular exercise program and not taking hormone replacement therapy. Additionally, participants should be non-smokers.

The study involves a supervised exercise program three times per week for eight weeks at the Medical Wellness Center. Participation in the study is provided at no cost to interested women who meet the above criteria and are able to complete the program. Benefits of the study include two DEXA scans, two complete fitness assessments and a supervised exercise program designed for weight loss.

If interested, please contact Lauren Tapp at 954-304-0432 or ltapp@temple.edu, or Joseph Signorile, Ph.D. at 305-284-3105 or jsignorile@miami.edu.


Study to Investigate Treatment to Reduce Phosphorous Intake for Chronic Kidney Disease Patients

If you have been diagnosed with chronic kidney disease (or chronic renal insufficiency), you may qualify for a research study that investigates a preventative treatment strategy that could delay complications related to chronic kidney disease. The three-month study includes: six short visits (30-60 minutes); three longer visits (three to four hours); blood draws, urine collection, oral glucose tolerance test, and echocardiogram; and taking an approved medication and/or modifying your diet. You must be 18 years of age or older. You will not be able to participate if you have problems with your liver or if you are pregnant. You will receive compensation and parking vouchers for all completed study visits. This study will be conducted at the Clinical Research Building at the University of Miami under the direction of Myles Wolf, M.D., in the Division of Nephrology and Hypertension of the University of Miami Miller School of Medicine. If interested, please call Gabriela Vargas at 305-243-4782 or e-mail at gvargas3@med.miami.edu.


Idiopathic Pulmonary Fibrosis Study to Test Effectiveness of Anticoagulant Drug

The Interstitial Lung Disease Research Program is enrolling patients with idiopathic pulmonary fibrosis for a new NIH study to assess the effectiveness of an anticoagulant. Treatment and evaluation will last a maximum of 144 weeks.

The primary endpoint of the trial is to demonstrate reduced time to composite endpoint (all-cause mortality, non-elective, non-bleeding hospitalization, or a decrease in absolute FVC of 10 percent or more). Secondary endpoints will include the difference in mortality, all-cause hospitalizations, global ranking, major bleeding events, acute exacerbations, respiratory-related hospitalizations, cardiovascular mortality or morbidity, cerebral vascular accident, venous thromboembolism, six-minute walk distance, quality of life assessments, DLCO and lung volumes, biological response monitoring between treatment and control groups and change in FVC. The clinical trial will be performed as part of the NIH National Heart Lung and Blood Institute-sponsored Idiopathic Pulmonary Fibrosis Clinical Research Network. Subjects must be between the ages of 35 and 80, have progressed despite conventional therapy and maintain a stable IPF treatment regimen.

For further information, please call 305-243-3728 or e-mail the study coordinator Emmanuelle Simonet at esimonet@med.miami.edu.


Idiopathic Pulmonary Fibrosis Study to Assess the Safety and Efficacy of N-Acetylcysteine

The Interstitial Lung Disease Research Program is enrolling patients with idiopathic pulmonary fibrosis for a new study to assess the safety and efficacy of N-acetylcysteine and the combination of prednisone, azathioprine and N-acetylcysteine in subjects with newly diagnosed idiopathic pulmonary fibrosis. Treatment and evaluation will last a maximum of 67 weeks. The primary endpoint of this trial is change in longitudinal forced vital capacity measurements over 60 weeks. Secondary endpoints will include change in dyspnea and occurrences of IPF exacerbations and respiratory infections. This clinical trial will be performed as part of the National Institutes of Health National Heart Lung and Blood Institute-sponsored Idiopathic Pulmonary Fibrosis Clinical Research Network. Subjects must be between the ages of 35 and 80, have a confirmed diagnosis of IPF with an FVC ≥ 50 percent and a DLCO ≥ 30 percent predicted.

For further information, please call 305-243-3728 or e-mail study coordinator Emmanuelle Simonet at esimonet@med.miami.edu.


Is your child anxious or depressed?

Does your teen seem anxious or depressed? Is fear or sadness causing your teen to avoid doing things he/she usually likes? The Child and Adolescent Mood and Anxiety Treatment (CAMAT) lab at the University of Miami is offering a free treatment program for teenagers (ages 12-17) who have an anxiety or depressive disorder.

• A parent must be available to accompany teens to all assessment sessions, as well as a few sessions during the treatment period.
• If eligible, the teen will receive between 8-21 treatment sessions with a trained clinician at the CAMAT program.

If you would like to learn more about how you can get help and hear more about the program, please contact the CAMAT lab at 305-284-9852 or anxietylab@psy.miami.edu.

In order to understand your child's particular feelings and behavior, after a free initial phone screening, a diagnostic assessment will be scheduled with one of our clinicians. If eligible, the study treatment will be offered free of charge.


CREATE Study on Internet Health Info

The Center for Research and Education on Aging and Technology Enhancement (CREATE) at the Miller School is conducting a research study involving the use of Internet health information in making health-related decisions. If you speak English and have some experience with the Internet you might qualify for this study. If you are interested in being part of this research study, please call 305-355-9200 and mention the Internet health information and decision-making study. You will be paid for your time and effort.


Grand Rounds
Thursday, September 30, 2010 7 a.m. Orthopaedic Grand Rounds: “Cartilage Injuries in the Talus”
Thursday, September 30, 2010 8 a.m. Otolaryngology Grand Rounds: “An Electrophysiological Intra-Operative Monitoring of Hearing During Ossiculoplasty"
Thursday, September 30, 2010 8 a.m. Neurological Surgery Grand Rounds: “Advances and Controversies in the Management of Pituitary Tumors"
Friday, October 1, 2010 1 p.m. Neurology Grand Rounds:  “Assessment of Rapidly Progressive Dementia and Early Diagnosis of Prion Disease"
Tuesday, October 5, 2010 12 p.m. Pathology Grand Rounds: “HPV Carcinogenesis in Head and Neck Tumors”
Wednesday, October 6, 2010 8 a.m. Family Medicine and Community Health Grand Rounds: “Global Health—The Haiti Experience”
Wednesday, October 6, 2010 12 p.m. Medicine Grand Rounds: “How Statisticians Think and Why it Annoys Doctors”
Thursday, October 7, 2010 7 a.m. Orthopaedic Grand Rounds: “Reverse Shoulder Replacement for Fractures and Their Sequelae”
Thursday, October 7, 2010 12 p.m. Department of Medicine Chair Dr. Marc Lippman Presents Pathology Grand Rounds
Thursday, October 7, 2010 12 p.m. Hospital Medicine Grand Rounds: “Providing Quality End-of-Life Care”
Thursday, October 7, 2010 1 p.m. Endocrinology, Diabetes and Metabolism Grand Rounds: “Molecular Regulation of RAGE: Implications for Diabetes and Beyond"
Friday, October 8, 2010 1 p.m. Neurology Grand Rounds: “Dense Array EEG”
Friday, October 8, 2010 2 p.m. Neurology Clinicopathological Conference: “A 61-Year-Old Male with Acute Onset Facial Diplegia, Diplopia and Dysphagia"
Tuesday, October 12, 2010 12 p.m. Cardiovascular Grand Rounds: “Contemporary Management of Paravalvular Leaks”
Wednesday, October 13, 2010 8 a.m. Family Medicine and Community Health Grand Rounds: “The Handoff of Hospitalized Patients”
Thursday, October 14, 2010 7 a.m. Orthopaedic Grand Rounds: “Doing Right and Avoiding Wrong in Orthopaedics Today”
Thursday, October 14, 2010 7:30 a.m. Surgical Grand Rounds: “Preparing for a Terrorist Threat: Defining the Role of the Surgeon”
Thursday, October 14, 2010 12 p.m. Hospital Medicine Grand Rounds: “Update in Obstructive Sleep Apnea”
Friday, October 15, 2010 1 p.m. Neurology Grand Rounds: “Creativity and the Brain”
Tuesday, October 19, 2010 12 p.m. Cardiovascular Grand Rounds: “Diagnosis and Therapy for Vulnerable Plaque”
Wednesday, October 20, 2010 12 p.m. Pathology Grand Rounds: “Thyroid FNA Cytology: Bethesda and Beyond”
Wednesday, October 20, 2010 12 p.m. Epidemiology and Public Health Grand Rounds: “A Randomized Controlled Trial of Structural Ecosystems Therapy for HIV+ Women in Drug Recovery and Their Families"
Wednesday, October 20, 2010 12 p.m. Psychiatry Grand Rounds: “Developmental Factors Underlying the Risk to Develop Anxiety and Depression"
Wednesday, October 20, 2010 12 p.m. Medicine Grand Rounds: “Management of HIV—Beyond HAART”
Wednesday, October 20, 2010 4 p.m. Special Miami Transplant Institute Grand Rounds Presentation and Celebration of 40 Years of Excellence
Thursday, October 21, 2010 7 a.m. Orthopaedic Grand Rounds: “The Biomechanical Rationale for Interosseous Ligament Reconstruction in Essex-Lopresti Injuries"
Thursday, October 21, 2010 7 a.m. Neurological Surgery Grand Rounds: “Surgical Management of Spine Tumors”
Thursday, October 21, 2010 8 a.m. Neurological Surgery Grand Rounds: “Neuropathology”
Thursday, October 21, 2010 8 a.m. Otolaryngology Grand Rounds: “Assessing the Levels of Obstruction in Sleep Apnea”
Thursday, October 21, 2010 12 p.m. Division of Hospital Medicine Grand Rounds: “A Man with Abdominal Pain and Jaundice”
Thursday, October 21, 2010 1:30 p.m. Endocrinology Grand Rounds: “Growth Hormone in Aging”
Tuesday, October 26, 2010 12 p.m. Cardiovascular Grand Rounds: “Carotid Stenting vs. Endarterectomy”
Wednesday, October 27, 2010 7:30 a.m. Plastic Surgery Grand Rounds: “Avoidance and Management of Complications in Lower Eyelid Surgery”
Wednesday, October 27, 2010 8 a.m. Family Medicine and Community Health Grand Rounds: “Promoting Smoking Cessation: Role of the Physician"
Wednesday, October 27, 2010 12 p.m. Department of Medicine Grand Rounds: “Clinical Empathy”
Thursday, October 28, 2010 7 a.m. Neurological Surgery Grand Rounds: “Biomarkers for CNS Injuries: From Benchside to Bedside”
Thursday, October 28, 2010 8 a.m. Otolaryngology Grand Rounds: “Nasal Osteotomy Techniques and Treatment of the Crooked Nose”
Thursday, October 28, 2010 8 a.m. Neurological Surgery/Neurology Grand Rounds: “Collateral Perfusion in Acute Ischemic Stroke”
Friday, October 29, 2010 1 p.m. Neurology Grand Rounds: “What Have We Learned From ADNI?”
Thursday, November 4, 2010 6:45 a.m. Anesthesiology Grand Rounds: “Postoperative Nausea and Vomiting: Can We Ever Get Rid of It?”
Events
Wednesday, September 29, 2010 9 a.m. The Miami Project Wednesday Morning Seminar: “Do Additional Inputs Change Maximal Voluntary Motor Unit Firing Rates After Spinal Cord Injury?"
Wednesday, September 29, 2010 12 p.m. Healthy Steps Presentation: “Clingy Children Who Won’t Let Go: Strategies to Help Your Child Overcome Separation Anxiety"
Thursday, September 30, 2010 12 p.m. Pediatric Clinical Research Forum: “The Incompatibility of Clinical Research and the Common Malady of P Value Neurosis"
Monday, October 4, 2010 12 p.m. Sylvester Comprehensive Cancer Center Seminar: “Target Identification and Inhibition in the Chronic Myeloproliferative Neoplasms"
Thursday, October 7, 2010 12 p.m. Research Roundtable: “Reporting System Overview”
Friday, October 8, 2010 12 p.m. Biochemistry and Molecular Biology Seminar: “Androgen Receptor Coregulators as Biomarkers and Therapeutic Targets in Prostate Cancer"
Friday, October 8, 2010 12 p.m. Ethics Seminar: “Getting to the Good Society—U.S. Research Priorities 2010-2020”
Friday, October 8, 2010 12 p.m. Friday Noon Interdisciplinary Lecture Series
Friday, October 8, 2010 1 p.m. Sylvester Distinguished Lecture: “The Role of Ubiquitination in Signaling Pathways in Inflammation and Cancer"
Tuesday, October 12, 2010 12 p.m. Cell Biology and Anatomy Seminar: “Basic Concepts in Cancer Histopathology”
Wednesday, October 13, 2010 9 a.m. Miami Project Wednesday Morning Seminar: “Recombinant Inhibitory Neuronal Progenitors in Models of Chronic Pain"
Wednesday, October 13, 2010 12 p.m. Pediatric Clinical Research Forum: “Early Detection of Kidney Disease in Preterm Infants”
Thursday, October 14, 2010 12 p.m. Molecular and Cellular Pharmacology Seminar: “Understanding the Molecular Basis of Angiogenesis for Therapy Design"
Thursday, October 14, 2010 12 p.m. Pathology Journal Club Meeting
Thursday, October 14, 2010 7 p.m. The Buoniconti Fund and the Miami Heat’s Chris Bosh Team Up with Neiman Marcus Coral Gables
Friday, October 15, 2010 12 p.m. Friday Noon Interdisciplinary Lecture Series: “Fragile X: A Family of Genetic Disorders”
Friday, October 15, 2010 1 p.m. Neuroscience Center Seminar: “Out on a Limb: Roles for EphA4 and SMN”
Monday, October 18, 2010 12 p.m. Microbiology and Immunology Seminar: “NF-kB Activation and Function: An Alternative View and New Insights Into NF-kB Function in the Nervous System"
Tuesday, October 19, 2010 12 p.m. Developmental Center for AIDS Research Seminar: “Mucosal Immune Responses in HIV Controllers: Location, Location, Location"
Tuesday, October 19, 2010 4 p.m. Genetics/Genomics Seminar: “Emerging Therapeutic Approaches to Mitochondrial Diseases”
Wednesday, October 20, 2010 7:30 a.m. Endocrinology Core Lecture: “Etiopathogenesis and Prevention of Type 2 Diabetes”
Wednesday, October 20, 2010 9 a.m. New Oral and Maxillofacial Surgery Office Opens at University of Miami Hospital
Wednesday, October 20, 2010 12 p.m. Pediatric Clinical Research Forum: “mAKAP and Cardiac Hypertrophy”
Thursday, October 21, 2010 1 p.m. Biochemistry and Molecular Biology Seminar: “Nutritional Modulation of Environmental Toxicity: Implications in Atherosclerosis"
Thursday, October 21, 2010 1 p.m. Endocrinology Fellows Clinical Case Conference: “The Diagnostic Challenges of Growth Hormone Deficiency"
Thursday, October 21, 2010 2:45 p.m. Endocrinology Research Conference: “Role of Type 3 Deiodinase (D3) in Pancreatic Islet Function”
Friday, October 22, 2010 12 p.m. Biochemistry and Molecular Biology Seminar: “Astroglial-NF-kB is an Important Regulator of Learning and Memory and Neurogenesis in Female Mice"
Saturday, October 23, 2010 3 p.m. Cancelled: Bike to the BankAtlantic Center
Sunday, October 24, 2010 10 a.m. 2010 Miami-Dade County “Out of the Darkness” 5K Walk for Suicide Prevention
Monday, October 25, 2010 10 a.m. Sylvester Comprehensive Cancer Center Seminar: “Bayesian Statistical Methods for the Design of Early Phase Cancer Trials and Analysis of Longitudinal Cancer Data"
Tuesday, October 26, 2010 12 p.m. Cell Biology and Anatomy Seminar: “ROS-Sensitive Association of Respiratory Complexes into Supercomplexes"
Tuesday, October 26, 2010 3:30 p.m. Anesthesiology Seminar: “Bedside to Bench: What Can We Learn About Migraine by Studying the Mechanisms of Action of Triptans?"
Wednesday, October 27, 2010 9 a.m. Miami Project Wednesday Morning Seminar: “Axon Formation”
Wednesday, October 27, 2010 12 p.m. Sylvester Distinguished Lecture: “Intracellular Antibodies as Inhibitors of Hepatitis C Virus Replication"
Wednesday, October 27, 2010 12 p.m. Healthy Steps Seminar: “School Readiness: Is Your Child Ready? Are You Ready?”
Wednesday, October 27, 2010 12 p.m. Pediatric Clinical Research Forum: “History of Whole Body Periodic Acceleration (WBPA) 1996-”
Wednesday, October 27, 2010 4 p.m. McKnight Research Seminar: “Deiminated REF Mediated mRNA Transport to Mitochondrial Surface in a Transgenic Mice Model of Multiple Sclerosis"
Thursday, October 28, 2010 8:30 a.m. Sylvester and University of Miami/Jackson Town Hall Meeting
Thursday, October 28, 2010 12 p.m. Brown Bag Lunch-and-Learn Seminar: “IRB 101”
Thursday, October 28, 2010 1:30 p.m. Molecular and Cellular Pharmacology and Division of Endocrinology to Host Seminar
Friday, October 29, 2010 9 a.m. The Miami Project to Cure Paralysis Seminar: “Brain-Machine Interfaces in Neuromedicine: Harnessing the Coding of Behavior from Neural Ensembles"
Friday, October 29, 2010 12 p.m. Biochemistry and Molecular Biology Seminar: “Structure and Function of Insect Odorant Receptors”
Friday, October 29, 2010 2 p.m. Neurology Clinicopathological Conference: “57-Year-Old Female with Progressive Lower Extremity Numbness"
Saturday, October 30, 2010 9 a.m. DOCS Little Haiti Health Fair
Saturday, October 30, 2010 10 a.m. 2010 Start! Heart Walk
Tuesday, November 2, 2010 12 p.m. Cell Biology and Anatomy Seminar: “Tissue Specific Control of Thyroid Hormone Action”
Wednesday, November 3, 2010 12 p.m. Gail F. Beach Memorial Visiting Lectureship: “Microglial Activation, Neuronal Death and Glial Regeneration After SCI"
Wednesday, November 3, 2010 12 p.m. Monthly Networking Meeting for Clinical Research Professionals
Friday, November 5, 2010 1 p.m. Neuroscience Center Seminar: “The Brain’s Logic for Storing Memories”
Monday, November 8, 2010 11 a.m. United Way Raffle Features Travel Prizes
Monday, November 8, 2010 4 p.m. Genetics/Genomics Seminar: “Genome Structure and Expression”
Friday, November 12, 2010 1 p.m. Sylvester Distinguished Lecture: “Cellular Phenotyping of Breast Tumors”
Saturday, November 13, 2010 8:30 a.m. College of Engineering and SEEDS Writing Workshop
Thursday, November 18, 2010 12 p.m. Office of Finance and Treasury 2010 United Way Silent Auction

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The University of Miami is an Equal Opportunity/Affirmative Action University.

Senior Vice President for Medical Affairs and Dean
University of Miami Miller School of Medicine
CEO, University of Miami Health System
Pascal J. Goldschmidt, M.D.

Executive Editor
Associate Vice President for Communications
Christine Morris

Editor
Jenny Prather

Contributors
Maya Bell
Dwayne Campbell
Jeanne Antol Krull
Lisa Worley


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