arrow   UM Miller School Honored by Hispanic Business

 

Around Campus
arrow new  New Grand Rounds Lecture Series
arrow new  UMMG Announces State-of-the-Art Paging and Emergency Broadcast System
arrow new  Vehicle and Phlebotomy Services Available
arrow Employee Assistance Program to Help Caregivers Communicate with Children
arrow Questions about Compliance? UM Helplines Can Assist You
arrow e-Update Submission Guidelines

Human Subjects Research Opportunities
For information on current Human Subjects Research Opportunities, see the listings below. There are new opportunities this week.

Feedback

Faculty and staff submissions should be e-mailed to the Office of Communications, at update@med.miami.edu.


Events
arrowUPCOMING
  Thursday, September 7, 2006, 7 to 8 a.m.
Guest Speaker at Orthopaedic Grand Rounds
  Thursday, September 7, 2006, 9 to 11 a.m.
Listening Skills for Supervisors
  Thursday, September 7, 2006, noon to 1 p.m.
Conversations About Cancer
  Monday, September 11, 2006, noon
Department of Microbiology and Immunology seminar presentation
  Tuesday, September 12, 2006, noon
new  Molecular and Cellular Pharmacology Seminars
  Wednesday, September 13, 2006, noon
new  Gail F. Beach Memorial 2006-2007 Visiting Lectureship Series
  Friday, September 15, 2006, 9 a.m. to 4 p.m.
new  Town Hall Meeting on Colorectal Cancer
  Tuesday, September 19, 2006, 2 to 4 p.m.
new  EAP Sponsoring Conflict Communication Skills Workshop
  Tuesday, September 19, 2006, noon to 1 p.m.
Human Subjects Protection Educational Seminar
  Thursday, September 28-October 1, 2006
Joint Cancer Conference of the Florida Universities
  Thursday, September 28, 2006, 12:30 p.m.
Frontiers in Vision Science Seminar

Peer Review
PUBLICATIONS
 Erin N. Marcus, M.D.,  assistant professor of clinical medicine, has published a Perspective article in the July 27 edition of The New...
e-update.med.miami.edu

 Back to top
UM Miller School Honored by Hispanic Business

The University of Miami Miller School of Medicine was ranked the fifth best medical school in the country for Hispanic students by Hispanic Business magazine. The results, published in the magazine’s September issue, were based on questionnaires that cover five categories:  enrollment, faculty, student services, retention rate and reputation. 

“As an institution, we value diversity and reflecting the community we serve, and for that reason we are proud to be in the top ranks of medical schools for Hispanic students,” said Pascal Goldschmidt, M.D.., senior vice president for medical affairs and dean of the Miller School of Medicine. “This honor reflects the commitment we have to the quality of our students and our faculty.”

Stanford University School of Medicine finished in the top spot, followed by University of Texas Health Science Center at San Antonio, University of Texas Medical Branch at Galveston and the University of New Mexico School of Medicine.

 “One of our educational priorities is training a culturally competent physician because we know that patients respond better to physicians who are like them and who understand them,” said Mark O’Connell, senior associate dean for medical education at the Miller School of Medicine. “We are proud to be recognized as one of the better institutions for meeting the goal of preparing doctors to be the best they can be in meeting society’s cultural needs.”


Around CampusBack to top
new  New Grand Rounds Lecture Series

The Jay Weiss Center for Social Medicine and Health Equity is pleased to announce the establishment of a grand rounds series on social medicine and health equity at the Miller School of Medicine.  The topics will focus on important questions, issues and case studies related to the emerging movement of social medicine and global health equity.  Speakers will be drawn from multiple disciplines, including medicine, public health, public policy, economics, anthropology, philanthropy and government.  Continuing medical education credits will be available to attendees as well as speakers.  The lectures will be available on live and archived webcasts at www.jayweisscenter.org.

The Grand Rounds will be held the first and third Tuesday of the month from October through May from noon to 1 p.m.  They will take place in the third floor auditorium of the Rosenstiel Medical Science Building unless otherwise noted.

The speakers will be drawn primarily from the University of Miami Miller School of Medicine, but will also include a number of visiting speakers throughout the year.

The Center's inaugural Grand Rounds will be delivered by Dean Pascal Goldschmidt on October 3.  He will speak on "Educating Doctors: The International Era.”  The second Grand Rounds in the series will be delivered by Harvard’s Paul Farmer, M.D., Ph.D.  His Grand Rounds is entitled, “Social Medicine in Practice: Examples from Africa and Latin America.” Seating will be limited for both of these events, so please arrive early.  

Please visit our website www.jayweisscenter.org for details about these Grand Rounds and the rest of the schedule for the year.  In addition, you may view the live webcast of the Grand Rounds on the website.

Please contact Maria Pieiga, 305-243-8893, or mpieiga@med.miami.edu if you have any questions.


new  UMMG Announces State-of-the-Art Paging and Emergency Broadcast System

The University of Miami Medical Group is pleased to announce the implementation of a state-of-the-art communications network which allows users to page providers via text/voice messages and view on-call schedules from any computer via the internet.

Benefits include: Web-based paging; speech-enabled answering services; broadcast services; on-call schedules – Web-based schedules can be updated from your desk. No need to distribute schedules – real time on-call calendar available to all departments on-line.

 Required training for on-call calendar managers is being held now. To enroll, log on to Net Learning at https://netlearning.miami.edu, select “On-Call Calendar Training,” and select “Enroll in Class.”


new  Vehicle and Phlebotomy Services Available

The Comprehensive Drug Research Center has vehicle and phlebotomy services available.  Two vans and one RV camper can be used to transport study participants or to conduct studies in the field.  They operate under a vehicle cost center.  The phlebotomy services also operate under a cost center or as a percentage of effort.  If you are interested in these services, please contact Sam Comerford at 305-243-7266.


Employee Assistance Program to Help Caregivers Communicate with Children

EAP presents "Systematic Training for Effective Parenting," an eight-week discussion group that offers caregivers a realistic and practical approach to meeting the challenges of raising kids today. The course focuses primarily on parenting children ages six to 12, but is open to all caregivers of children. The course will be offered on the medical campus beginning in September. For locations, dates, and to register, visit http://netlearning.miami.edu.  Note that you must register for each of the eight days that it meets. For questions about registration, call  305-243-5110 or 305-243-3090 . For questions about content, call 305-284-6604 or visit www.miami.edu/eap and click on "Seminar Schedule."   


Questions about Compliance? UM Helplines Can Assist You
  • University Compliance (anonymous hotline): 866-YOURCALL
  • Billing (anonymous hotline): 305-243-HELP or 877-415-HELP
  • Research Integrity and Compliance: 305-243-6415
  • Financial Improprieties: 305-284-2605
  • Privacy Office/HIPAA: 305-243-5000 or 1-866-366-HUSH
  • University Ombudsperson: 305-284-4922

Any University of Miami employee reporting or deciding whether to report activity that may be in violation of a law, rule, or regulation is protected against retaliation by the Whistleblower Protection Statement. For more information, visit the Office of Compliance site.


e-Update Submission Guidelines

  • Please note that submissions are due no later than 5 p.m. Thursday for publication on Tuesday.
  • We are unable to include attachments.
  • Please use URL addresses in your announcements rather than hyperlinks.
  • Event announcements should include the time, date, location, speaker, topic and cost if applicable. All events should have a contact phone number or e-mail address for further information. We will run event announcements for three weeks only.
  • Information must be written in paragraph form. PDFs, Publisher files and flyers are not accepted.
  • Human Subject recruitment announcements must be IRB approved.
  • Events to be listed should be either held on the medical campus, sponsored or hosted by the Miller School of Medicine, or affect all or most of the employees on the medical campus.
  • Please be sure to e-mail items to e-Update at update@med.miami.edu. Submissions to other e-mail addresses run the risk of being missed.


EventsBack to top
Guest Speaker at Orthopaedic Grand Rounds
September 7, 2006, 7 to 8 a.m., Mailman Center eighth-floor auditorium

Hari Parvataneni, M.D., will be the guest speaker at Orthopaedic Grand Rounds on Thursday, September 7 from 7 to 8 a.m. in the Mailman Center eighth-floor auditorium.  Parvataneni, an orthopaedic surgery fellow at Massachusetts General Hospital, will be speaking on "Soft Tissue Balancing and Mechanical Principles of Total Knee Arthroplasty." Objectives include understanding reconstruction goals of total knee replacement, early modes of failure of total knee replacement, and optimization of component position and soft tissue balance.


Listening Skills for Supervisors
September 7, 2006, 9 to 11 a.m., Dominion Towers Parking Garage, suite 155

Due to last week's storm, the seminar "Listening Skills for Supervisors" has been rescheduled to this Thursday, from 9 to 11 a.m., at Dominion Towers Parking Garage, suite 155.

Frontline supervisors can learn more about adjusting their listening behaviors during a leadership academy course. This course is designed to teach individuals to actively listen in a variety of situations, listen for different types of input and respond appropriately, and distinguish between pertinent and impertinent information.

Participants will complete an assessment and computer based learning,a prerequisite for enrolling in the live session, then attend a live classroom presentation and explore situations that call for diverse forms of listening.  After completing the assessment and CBL, participants are encouraged to develop their own learning objectives for the live training and will be able to put newly-gained skills into practice.

The instructor will be Mary Remon from EAP. For more information, call 6-3090 or check www.netlearning.miami.edu.


Conversations About Cancer
September 7, 2006, noon to 1 p.m., UM/Sylvester, room 1301; UM/Sylvester at Deerfield Beach, 1192 East Newport Center Drive, suite 100 for the September 12 lunchtime presentation; The Wellness Community, 8900 South Dixie Highway for the September 12 dinner presentation

The following presentations take place from noon to 1 p.m. They are free and a light lunch will be served. RSVP is required. Please call 1-800-545-2292 to register.

Talia Donenberg, M.S., will discuss "Gynecologic Cancer Genetics" on Thursday at UM/Sylvester.

Aaron H. Wolfson, M.D., will discuss "Radiation Oncology" on Monday, September 18 at UM/Sylvester.

Talia Donenberg, M.S., will discuss “Genetics and Cancer" at UM/Sylvester at Deerfield Beach.

The following presentation will take place at The Wellness Community, 8900 South Dixie Highway, from 6:30 to 8:30 p.m. Dinner will be served. Reservations are required; please call 1-800-545-2292.
 
Denise Pereira, M.D., will discuss "Lymphoma-Blood Cancers"
on Tuesday, September 12.


Department of Microbiology and Immunology seminar presentation
September 11, 2006, noon, RMSB 3109

FOX P-3 Molecules and Bone Marrow Derived Regulatory Cells in Renal Transplantation: Do They Help Light the Way to Tolerance, or Was Medawar Wrong? This presented will take place in RMSB 3109 by Joshua Miller, MD, professor in the department of surgery at noon on Monday, September 11.


new  Molecular and Cellular Pharmacology Seminars
September 12, 2006, noon, Rosenstiel Medical Science Building, room 6018

Pedro J.I. Salas, M.D., Ph.D., associate professor in the Department of Cell Biology and Anatomy at the Miller School of Medicine, will present “Apical Positioning of Microtubule-Organizing Centers in Simple Epithelia, a Novel Function of Intermediate Filaments,” as part of the Molecular and Cellular Pharmacology Seminars series on Tuesday, September 12 at noon in RMSB, room 6018. For more information, please call the Department of Molecular and Cellular Pharmacology at 305-243-5909.


new  Gail F. Beach Memorial 2006-2007 Visiting Lectureship Series
September 13, 2006, noon, Lois Pope LIFE Center seventh-floor auditorium

The Gail F. Beach Memorial 2006-2007 Visiting Lectureship Series will host John Steeves, Ph.D., professor, British Columbia Leadership Chair and Director of the International Collaboration on Repair Discoveries ( ICORD).  He will present "Challenges of Clinical Translational Research in SCI: Who, What, Where, When, Why and Let’s Not Forget, How!” on Wednesday, Sept. 13 at noon in the Lois Pope LIFE Center seventh-floor auditorium. For more information, call 305-243-7108 or visit us online at: www.miamiproject.med.miami.edu/x381.xml.


new  Town Hall Meeting on Colorectal Cancer
September 15, 2006, 9 a.m. to 4 p.m., Diagnostic Treatment Center, Jackson Memorial Hospital, room 259

The University of Miami Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital will host a town hall meeting on colorectal cancer on September 15 at JMH. It will run from 9 a.m. to 4 p.m. in the Diagnostic Treatment Center, room 259, and is free and open to the public and includes lunch. Speakers include cancer surgeons, radiation and medical oncologists, and colon cancer survivors. Topics include diagnosis and treatment of colorectal cancer, determining family history and genetic risk, what to expect from diagnosis through treatment, and tips to reduce risk. For more information please call 305-585-6038.


new  EAP Sponsoring Conflict Communication Skills Workshop
September 19, 2006, 2 to 4 p.m., Dominion Towers Parking Garage, room 155

Participate with the Employee Assistance Program (EAP) in a workshop designed to help attendees learn to communicate more effectively in conflict situations.  The course is designed in a blended format, combining a prerequisite online computer-based training component with a live workshop where participants can strengthen their skills through practice. It will be held on the medical campus on Tuesday, September 19, from 2 to 4 p.m. in Dominion Parking Garage, room 155. 

To register, visit http://netlearning.miami.edu.  For easy step-by-step instructions on how to register, visit http://www.miami.edu/eap/HowToRegister.doc.  For answers about registration, contact 305-284-5110 (Gables/Rosenstiel) or 305-243-3090 (Medical). For answers about content, call the EAP at 305-284-6604.  Supervisors are encouraged to post this notice for employees who do not have electronic access.


Human Subjects Protection Educational Seminar
September 19, 2006, noon to 1 p.m., Mailman Center, room 3023

"Question and Answer Session on the Use of Electronic Records in Research" will be discussed during the next Human Subjects Protection Educational Seminar. The event is set for Tuesday, September 19, at the Mailman Center, room 3023 from noon to 1 p.m.  Presenters include  Kathy Roach, office of research compliance assessment, and Audra Lazarus, assistant general counsel.  Registration through NetLearning at: https://netlearning.miami.edu.

For further details, please contact mvalero@med.miami.edu.


Joint Cancer Conference of the Florida Universities
September 28-October 1, 2006, Breakers Hotel, Palm Beach

The Joint Cancer Conference of the Florida Universities will be held September 28 through October 1 at The Breakers Hotel in Palm Beach. For more information, visit www.jcc-fl.org or call Claire A. Modarelli at 888-456-2840 or 813-745-7252.


Frontiers in Vision Science Seminar
September 28, 2006, 12:30 p.m., Bascom Palmer Eye Institute's Retter Auditorium

Badri Roysam, DSc., from Rensselaer Polytechnic Institute, will be the guest speaker at Bascom Palmer Eye Institute’s Frontiers in Vision Science Seminar on Thursday, September 28, at 12:30 p.m.  Roysam will be speaking on "Bayesian Approaches to Automated Analysis of Changes in Retinal Images," in Bascom Palmer Eye Institute's Retter Auditorium. A lunch reception will begin at noon in front of the auditorium. For more information, please contact Johnny Y. Shum at 305-326-6047, or e-mail jshum@med.miami.edu.


Peer ReviewBack to top

Publications

Erin N. Marcus, M.D., assistant professor of clinical medicine, has published a Perspective article in the July 27 edition of The New England Journal of Medicine.  The article titled "The Silent Epidemic ­ The Health Effects of Illiteracy," examines the impact of reading problems on adults' health.


Human Subjects ResearchBack to top

The Department of Psychiatry and Behavioral Sciences is conducting a federally funded HIV behavioral intervention research study for women and their partners, the New Opportunities for Women 2 (NOW 2) Project. The project will address topics related to safer sex, sexual risk reduction, STDs and communication skills. The NOW 2 Project is currently recruiting English-speaking couples, in which one or both individuals must be HIV positive. Participants must be 18 years or older, willing to be tested for STDs, and answer personal questions in a confidential interview. Women and men who participate may each receive compensation of up to $360 for an entire year of participation (this includes attendance at all interviews, examinations and sessions). If interested, please contact Arnetta Phillips or Jackie Gomez, at 305-243-2103, or (aphillips@yahoo.com / jgomez4@med.miami.edu).

 

The Center for Liver Diseases is recruiting participants for the following studies:

Patients with cirrhosis of the liver as a result of Hepatitis B Infection:

This is a phase III b protocol comparing entecavir vs. adefovir in chronic hepatitis B subjects with evidence of hepatic decompensation. Subjects must have cirrhosis because of hepatitis B infection, never been treated for hepatitis B or treated with lamivudine (epivir) only, and do not have HIV, hepatitis C or D. For further information please call: 305)-243-6939, or e-mail the study coordinator, Connie Higgins at: chiggins@med.miami.edu.

Chart review:

This study is a chart review on hepatitis B subjects to determine the relation of an elevated HBV DNA and normal liver function tests to the histological findings of the liver biopsy. The study requires the subject has a previous liver biopsy between 2003-2006 and to see the research team to obtain a hepatitis B serology panel, liver function tests (ALT and AST), and HBV viral load. Subjects must be more than 18 years old, have a documented laboratory diagnosis of HBV infection of at least six months, treatment naïve patient, had a previous liver biopsy done between 2003-2006, and a documented HBV DNA. The previous biopsy slides will be retrieved and sent to a central reviewer. If you are interested, please contact University of Miami Center for Liver Diseases, Zvi Leibovici at 305-243-2330, or e-mail at zleibovici@med.miami.edu.

 

• Patients with hepatic encephalopathy
This study will compare Lactulose and Rifaximin to determine the benefit of either drug, or a combination of both. We will be enrolling patients with cirrhosis of the liver and a history of a previous hospitalization for hepatic encephalopathy. Patients will be followed for six months and a one-month post-treatment. Contact Macy Ho, CRC 305-243-4648 or e-mail Mho@med.miami.edu.

• Patients with chronic liver disease
This studies the correlation between liver histology and elasticity measured in patients with chronic liver disease using a device known as Fibroscan. This is a painless, non-invasive test. Qualifying patient must have received a laparoscopic liver biopsy within the past two months or scheduled a laparoscopic liver biopsy within the next two months by their PCP at Cedars Medical Center-Miami. This is a one time visit. Liver cancer patients are excluded. Contact: A. Brown at 305-243-2184 or abrown@med.miami.edu

Vaccine test in patients with chronic hepatitis C.
The Center for Liver Diseases is conducting a Phase I, double-blind, placebo controlled, dose escalation, multi-center trial of a therapeutic vaccine in patients with chronic hepatitis C infection. Subject must be > 18, have no hypersensitivity to baker's yeast, non-cirrhotic, compensated liver disease, and must have received a liver biopsy within the past two years or be willing to have one performed. Subjects can be naïve to previous treatment, or a relapser or partial responder to an interferon-based treatment. Must meet other criteria as well. Contact A. Brown at 305-243-2184 or abrown@med.miami.edu

• Study of three treatments
The Center for Liver Diseases is conducting a phase 2, double-blind, multi-center, randomized research study in HBV decompensated subjects. Adult subjects with CPT score of 7-12 and no history of HCC will be assigned to one of the three treatment arms: Tenofovir Disoproxil Fumarate (TDF), Emtricitabine plus Tenofovir Disprocil Fumarate (FTC/TDF) or Entecavir (ETV). Patients can be on lamivudine or adefovir dipivoxil. Must meet other criteria. Contact Clinical Research Coordinator Karina Herrera at 305-243-2148 or at kherrera@med.miami.edu 

• Study of liver diseases
The Center for Liver Diseases is conducting a Phase II study for men and women, investigational oral medication for liver scarring caused by chronic Hepatitis C. Subjects must be between 40 and 70 years old, have been diagnosed with chronic Hepatitis C, have failed prior Hepatitis C therapy with interferon and ribavirin treatments, which must have been discontinued at least 12 months ago. Study staff will review additional criteria if you are interested in learning more. The study should last approximately 56 weeks with 14 clinic visits. Contact Macy Ho, CRC 305-243-4648 or Mho@med.miami.edu

Do you or does someone you know experience pain related to spinal cord injury? Eva Widerström-Noga, Ph.D., and her colleagues are conducting research into the nature and treatment of pain associated with spinal cord injury. Studies are enrolling now.  Eligible participants will be 18 to 70 years of age and at least two years post-injury.  If you are interested in enrolling, please call The Miami Project to Cure Paralysis at 305-243-8132 for information.

The Center for Liver Diseases is conducting a phase 2, double-blind, multi-center, randomized study in HBV decompensated subjects. Adult subjects with CPT score of 7-12 and no history of HCC will be assigned to one of the three treatment arms: Tenofovir Disoproxil Fumarate (TDF), Emtxticitabine plus Tenofovir Disoproxil Fumarate (FTC/TDF) or Bntecavir (ETV). Patients can be on lamivudine or adefovir dipivoxil. Must meet other criteria. For further information, please contact clinical research coordinator Karina Herrera at 305-243-2148, or at kherrera@med.miami.edu.

Heather Woolery-Lloyd, M.D., of the Division of Cosmetic Dermatology, is looking for people between the ages of 18 and 39 who have mild to severe acne to participate in a research study to determine whether use of an investigational topical treatment will improve acne.  If you are interested, please contact a member of the research staff at 305-531-5788.

The Department of Psychology is recruiting participants for the following studies:

• A schizophrenia family study 
Have you or one of your relatives been diagnosed with schizophrenia or schizoaffective disorder? Are you in regular contact with this person? If so, you and your family may be eligible to participate in a free family-focused treatment research study. During the treatment, clinicians will provide factual information about schizophrenia and schizoaffective disorder. In addition, techniques to assist the family in coping with mental illness will be presented. Treatment is available in English and Spanish. If interested, please contact the Schizophrenia Family Project at 305-284-5455.

• A family factors and autism study
The aim of this project is to better understand families’ emotional reactions to autism spectrum disorders. We seek the participation of adults with high-functioning autism or Asperger’s and one of his or her parents. Participation will involve one hour-long telephone call. If you would like to help with this study or if you have any questions, please contact Stephanie Wasserman at 305-284-2307.

Researchers at the MRI Center need healthy subjects for a magnetic resonance imaging study. For more information, please visit http://midas.med.miami.edu/Research/MRStudies.htm.

Patients with idiopathic pulmonary fibrosis (IPF) are being recruited for a study of effects of sildenafil on exercise and breathlessness. Participants must have a firm clinical diagnosis of IPF, be 40 to 85 years of age, and not be on medication for IPF. Interested patients or physicians wishing to refer patients should call 305-575-3548, fax 305-575-3126, or e-mail rjackson2@med.miami.edu.

The Department of Obstetrics and Gynecology is testing experimental medications and therapies for the treatment of cervical dysplasia, a pre-cancerous condition that can lead to cancer if left untreated. Current treatments are surgical or invasive. This study is testing an investigational gene therapy to see if it safely and effectively treats HPV medicated cervical lesions as a result of dysplasia. If you are between 18 and 25 and have had an abnormal PAP test, you may be able to take part in this research study. Qualified participants will receive all study-related care and study therapy. To find out more, call Iliana Rivas at (305) 243-5832 or i.rivas@miami.edu

The Department of Psychology and the Division of Cancer Prevention and Control is conducting a quality of life research intervention with advanced prostate cancer patients. Participants should have Stage III or IV prostate cancer and have recently or currently been treated with hormone therapy. Eligible participants will take part in a ten-week cognitive behavioral stress and affect management program or a health promotions program. Three psychosocial/medical assessments are also required. If you are interested in this study or would like more information, please contact Frank Penedo, Ph.D., at 305-243-3329, or fpenedo@miami.edu.

Daniel Santisteban, Ph.D., of the Center for Family Studies in the Department of Psychiatry and Behavioral Sciences, is currently conducting a research program that would provide adolescents and/or their family treatment for free. Participants must be 14 to 17 years old, have a parent or legal guardian willing to participate, meet DSM criteria for both substance abuse disorder and borderline personality disorder, and be willing to participate in four separate but paid evaluations. If interested, please contact Henry Calderon, clinical research specialist/assessor, at 305-243-2225, or hcalderon@med.miami.edu for details.

The Center for Research and Education on Aging and Technology Enhancement is conducting research with family caregivers of dementia patients who speak English and are 50 years of age or older. If you are not a caregiver but are interested in participating, you may be able to help as well. Participants will receive basic training on how to use the Internet and will be asked to look for information about care-giving and dementia. If you are interested in being a part of this research study, please call 305-355-9200. You will be paid for your time and effort.

Jennifer B. Marks, M.D., is currently recruiting patients ages 18 through 40 with type 1 diabetes mellitus with a recent diagnosis for participation in a research study to test the safety and effectiveness of an investigational medication. Patients must be taking multiple insulin injections daily and in good health. Those who are interested should contact Rogelio Suarez at 305-243-6573 or rsuarez2@med.miami.edu.

The AIDS Clinical Research Unit, directed by Margaret Fischl, M.D., is recruiting participants for the following studies:

• A phase I IL-7 study (IL-7 is a cytokine that aids T-cell development and improves T-cell survival). Participants must be 18 to 50 years of age, receiving antiretroviral therapy for at least 12 months, have an HIV-1 RNA level less than or equal to 50,000 copies/ml, and have a CD4 cell count of 100 cells/ccm or higher. Participants must be willing to do 12-hour IL-7 blood level monitoring. Up to $200 in food certificates provided.

• An investigational CC-chemokine receptor 5 (CCR5) entry inhibitor for patients with HIV. The study will look at single dose, dose escalations of a study drug (0.5 mg, 2.0 mg and 5.0 mg) and a placebo. The study will determine how well the study drug blocks CCR5 receptors and is tolerated. Participants must be 18 and older, not taking antiretroviral therapy for at least three months and have a viral load greater than 5,000 and a CD4 count greater than 250. Must be willing to do six-hour drug level monitoring. Up to $250 provided.

For more information on studies conducted by the AIDS Clinical Research Unit, contact Juan at 305-243-3838 or Leslie at L.Thompson@miami.edu.

The SPARE Study (Soy Phytoestrogens As Replacement Estrogen) is currently recruiting women 45 to 60 years of age to study the role of soy phytoestrogens given in tablet form to prevent bone loss. Participants will be given a physical exam at study entry, an annual mammogram and bone density test, and will be asked to come for 10 study visits over a period of two years for blood tests and to complete questionnaires about diet, exercise, and well-being. Interested women should contact the SPARE Study Office at 305-243-4330 or via e-mail at aherrin@med.miami.edu.

The University of Miami Skin Research Group, directed by Brian Berman, M.D., Ph.D., is looking for people with acne, atopic dermatitis (eczema), and keloids. Participants should be 18 or older for the acne and keloid studies and ages 2 to 17 for the atopic dermatitis studies. If interested, please contact the research staff at 305-243-5519 or visit our website at www.skininvestigation.com.

Bruce Rubin, M.D., is currently performing a study on trigeminal neuralgia (TN) treatment with subcutaneous injections of BOTOX® to evaluate the effectiveness of treating facial pain associated with TN. Patients must have a diagnosis of TN for more than three months and be at least 18 years of age.
 
Dr. Rubin is also seeking patients for a research study on the treatment of tightness/spasticity in the wrist, fingers, and elbow caused by a stroke while evaluating the effect of BOTOX® on pulmonary functioning. Patients must be 18 years of age, have had a stroke six months ago or longer, have a pulmonary/breathing problem and cannot have used BOTOX® or any other botulinum toxin previously for any condition. Please contact Amy L. Kaye, ARNP, at 305-243-6223 for additional information on either of these studies.

 

 


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